TB-500
A synthetic fragment of Thymosin Beta-4, the body's own repair protein. People run it for whole-body recovery, for tendon, ligament, and muscle repair, and for flexibility, often alongside BPC-157 after a nagging injury.
Where to buy TB-500, cheapest first.
Prices from 6 vendors across the market. We link straight to each vendor’s product page and grade vendors on public lab data, so you’re not just chasing the lowest number.
TB-500
What TB-500 actually does.
The simple version first, then a little more for the curious. No biochem degree required.
It tells your body to repair tissue everywhere at once, building new blood vessels and helping cells migrate to where they're needed, so injuries recover faster.
How it works
TB-500 is the active region of Thymosin Beta-4. It regulates actin, the protein that lets cells move and rebuild, triggers angiogenesis (new blood vessels), and calms inflammation, so damaged tissue repairs faster.
Where it acts
Instead of acting in one spot, it travels through the bloodstream and works body-wide, studied for muscle, tendon, ligament, and even cardiac and nerve tissue. That's why people run it for whole-body recovery.
What people notice
After an injury or a hard training block, people report faster recovery, better range of motion, and less nagging stiffness. Effects tend to build over weeks, not hours.
Honest caveat: most of this comes from animal and lab studies. The strongest human evidence is on full-length Thymosin Beta-4 in topical and eye formulations, not the injectable TB-500 fragment. It is not an approved medicine and is sold strictly for research use only. None of this is medical advice, talk to a licensed provider before starting anything.
How to take it.
TB-500 is an injection, given subcutaneously into fat or intramuscularly near a target area with a tiny insulin needle. It isn't a meaningful oral peptide, so the injectable form is what people run. The routine is below; for cycling and timing, see the full guide.
Reconstitute the vial
Add bacteriostatic water down the side of the vial (a 10mg vial + 2mL = 5mg/mL). Let it dissolve. Swirl gently, don't shake.
Draw your dose
On a U-100 insulin syringe, pull to your unit mark. 2.5mg at 5mg/mL is 50 units (0.5mL). Use the calculator if you're unsure.
Pinch and inject
Swab with alcohol, pinch a bit of fat, insert at 45–90°, push slowly. Subcutaneous into the belly is simplest; some people go intramuscular nearer the area they're targeting.
Rotate your sites
Move to a different spot each time so no area gets sore or lumpy. Store the vial in the fridge between doses.
The easiest spots are the belly (about 2 inches either side of the navel), the love handles, the front of the thigh, and the back of the upper arms. Rotate every injection.
Don't do the math, let the calculator do it.
This is TB-500's typical setup, already worked out. Change any value and the draw updates instantly.
Typical TB-500 dose: about 2.5 mg twice a week during a loading phase of roughly six weeks, then 2.5 mg once a week to maintain. It's run in cycles, not continuously.
How to cycle TB-500.
How long people run TB-500, when to take a break, and the honest reasoning behind it.
A loading phase, then a lower weekly maintenance dose.
A cycle just means a defined run of time on the peptide, followed by a break. For TB-500 the common pattern is a loading phase of roughly six weeks, then a lighter weekly maintenance dose, then time off, rather than running it indefinitely.
Why not just run it forever? Mostly because the long-term human safety data does not exist yet. The cautious and widely followed approach is to run a focused block while you are recovering, then stop.
- Hold the schedule through your loading weeks, twice a week, at roughly even spacing.
- Step down, do not just quit cold if you want to maintain, moving to once weekly after the loading phase.
- Take a real break after a cycle before considering another. If symptoms return, that is a conversation for a licensed provider.
Want the full picture, on and off periods, the washout, stacking, and keeping your results? Read how peptide cycling works →
What's actually in the vial.
For 4 of these vendors we link the per-batch certificate itself (a specific lab report, COA PDF, or certificate image), and the purity below is read straight off that certificate. The rest link to the vendor's general lab-results page. We don't run the labs ourselves and we don't show a purity number unless it's printed on a certificate we link, so you can open the document and check it against the batch yourself.
| Vendor | Purity (per COA) | Batch / report | Certificate |
|---|---|---|---|
| EZ Peptides | 99.872% | EZP-TBF1004082026-04 | Janoshik report ↗ |
| Swiss Chems | 99.65% | AY5434 | View COA ↗ |
| Pure Rawz | 99.6% | PRWZ-098 | View COA ↗ |
| Midwest Peptide | 99.11% | MPTB001 | View COA ↗ |
| Next Gen Peptides | see lab page | not shown | Lab results ↗ |
What people pair it with.
TB-500 is rarely run alone. These are the combinations the community reaches for when recovery is the goal.
Recovery & repair
One shot that covers the whole recovery cascade, tissue and tendon repair, gut and skin support, and calmer inflammation. The all-in-one healing blend.
View stack →Injury & healing
The go-to soft-tissue pair. BPC-157 works locally on tendons, ligaments, and the gut lining; TB-500 helps the whole body recover and move better.
View stack →Skin & recovery
The repair stack people run for skin as well as tissue. GHK-Cu adds the copper-peptide angle for skin and collagen on top of the healing base.
View stack →In the same corner.
Other healing and recovery peptides people compare against TB-500.
Questions, answered straight.
Is TB-500 legal?
TB-500 isn't an approved drug, and it isn't sold for human use. The vendors we compare offer it strictly for research use only. It's also on WADA's prohibited list, so competing athletes should steer clear. Rules vary by country, so check what applies where you are.
What does research use only actually mean?
It means the product is sold for laboratory and research purposes, not as a supplement or medicine for people. It hasn't been reviewed or approved for human use by the FDA. We aggregate prices and public lab data so you can see the landscape; what you do with that is between you and a licensed provider.
How do I store it?
Keep the sealed, freeze-dried vial in the fridge, and out of direct light. Once you mix it with bacteriostatic water, store it refrigerated and use it within a few weeks. Don't freeze a reconstituted vial.
How often do people dose it?
A common pattern is about 2.5 mg twice a week during a loading phase of roughly six weeks, then 2.5 mg once a week to maintain. People run it in cycles rather than continuously. Use the calculator to turn your vial and dose into exact units.
Subcutaneous or intramuscular?
Either works. Subcutaneous into the abdomen is the simplest and most common; some people inject intramuscularly nearer a specific area. After reconstitution it's the same draw either way. TB-500 isn't an oral peptide, so skip the capsule versions.