A long-acting analog of growth-hormone-releasing hormone (GHRH). People run it to nudge their own pituitary into releasing more growth hormone, usually for lean mass, recovery, and sleep, and it is almost always paired with Ipamorelin.
Prices from 7 vendors across the market. We link straight to each vendor’s product page and grade vendors on public lab data, so you’re not just chasing the lowest number.
The simple version first, then a little more for the curious. No biochem degree required.
It tells your own pituitary to release more growth hormone, in natural pulses, instead of injecting growth hormone directly. The result builds slowly through higher GH and IGF-1.
CJC-1295 is a modified GHRH peptide. It binds the GHRH receptor on the pituitary and increases the size of your natural growth hormone pulses, which in turn raises IGF-1. It is a secretagogue, meaning it asks the body to make its own GH rather than replacing it.
Two forms exist. CJC-1295 with DAC binds to albumin and lasts 6 to 8 days, so it is dosed weekly. CJC-1295 without DAC, often called Mod GRF 1-29, clears in under two hours, so it is dosed daily and pairs cleanly with Ipamorelin.
Because it works through your own GH pulses, effects build over weeks: deeper sleep first, then gradual changes in recovery, body composition, and skin. It is not a fast or dramatic compound.
Honest caveat: human evidence is thin. The main controlled trials ran 28 to 84 days in small groups and showed CJC-1295 raises GH and IGF-1, but real-world outcomes like muscle gain and fat loss are mostly extrapolated, not proven. It is not an approved medicine and is sold strictly for research use only. None of this is medical advice, talk to a licensed provider before starting anything.
CJC-1295 is an injection, given subcutaneously into fat with a tiny insulin needle. It is not an oral peptide, so the injectable form is what people run. The no-DAC version is dosed daily, usually with Ipamorelin; the DAC version is dosed weekly. The routine is below; for cycling and timing, see the full guide.
Add bacteriostatic water down the side of the vial (a 5mg vial + 2mL = 2.5mg/mL). Let it dissolve. Swirl gently, don't shake.
On a U-100 insulin syringe, pull to your unit mark. A 100mcg dose at 2.5mg/mL is 4 units (0.04mL). Use the calculator if you're unsure.
Swab with alcohol, pinch a bit of fat, insert at 45–90°, push slowly. Subcutaneous into the belly is simplest. For the no-DAC form, dose on an empty stomach, ideally before bed.
Move to a different spot each time so no area gets sore or lumpy. Store the vial in the fridge between doses.
The easiest spots are the belly (about 2 inches either side of the navel), the love handles, the front of the thigh, and the back of the upper arms. Rotate every injection.
This is CJC-1295's typical setup, already worked out. Change any value and the draw updates instantly.
Typical CJC-1295 dose: for the no-DAC form, about 100 mcg once or twice daily, usually paired 1:1 with Ipamorelin, on an empty stomach. For the DAC form, about 1 to 2 mg once a week. It's run in cycles, not continuously.
How long people run CJC-1295, when to take a break, and the honest reasoning behind it.
Run in cycles, usually stacked with Ipamorelin.
A cycle just means a defined run of time on the peptide, followed by a break. For CJC-1295 the common pattern is a block of roughly 8 to 12 weeks, then time off, rather than running it indefinitely.
Why not just run it forever? Mostly because the long-term human safety data does not exist yet, and because chronically elevated GH and IGF-1 carry theoretical risks. The cautious and widely followed approach is to run a focused block, then stop and reassess.
Want the full picture, on and off periods, the washout, stacking, and keeping your results? Read how peptide cycling works →
For 5 of these vendors we link the per-batch certificate itself (a specific lab report, COA PDF, or certificate image), and the purity below is read straight off that certificate. The rest link to the vendor's general lab-results page. We don't run the labs ourselves and we don't show a purity number unless it's printed on a certificate we link, so you can open the document and check it against the batch yourself.
| Vendor | Purity (per COA) | Batch / report | Certificate |
|---|---|---|---|
| EZ Peptides | 99.095% | EZP-CJC0505232026-05 | Janoshik report ↗ |
| Ion Peptide | 99.977% | CD5-04022026 | View COA ↗ |
| Swiss Chems | 99.84% | CY-15A | View COA ↗ |
| Midwest Peptide | 99.42% | MPCJ001 | View COA ↗ |
| Pure Rawz | see COA | not shown | View COA ↗ |
| Penguin Peptides | see lab page | not shown | Lab results ↗ |
CJC-1295 is rarely run alone. These are the combinations the community reaches for when growth hormone support is the goal.
The gold-standard pairing. CJC-1295 raises the size of each GH pulse while Ipamorelin triggers the pulse itself. Dosed 1:1, usually 100 mcg each before bed. The combination people start with.
View stack →The GH pulse stack with BPC-157 layered in for soft-tissue and gut repair. People run it during a hard training block or while working through a nagging injury.
View stack →A GH-leaning blend for people focused on body composition. Tesamorelin adds a second GHRH analog studied specifically for visceral fat. An advanced combination, not a starting point.
View stack →Other growth hormone and muscle peptides people compare against CJC-1295.
CJC-1295 isn't an approved drug, and it isn't sold for human use. The vendors we compare offer it strictly for research use only. It's also on WADA's prohibited list as a growth hormone secretagogue, so competing athletes should steer clear. Rules vary by country, so check what applies where you are.
DAC stands for Drug Affinity Complex. The DAC version binds to albumin in your blood and lasts 6 to 8 days, so it's dosed once a week. The no-DAC version, sometimes called Mod GRF 1-29, clears in under two hours, so it's dosed daily and pairs cleanly with Ipamorelin to mimic natural GH pulses. Most modern protocols use the no-DAC form.
They work on two different switches. CJC-1295 increases how much growth hormone each pulse releases, while Ipamorelin triggers the pulse to happen. Together they produce a stronger, cleaner GH release than either alone, which is why the pair is the standard starting stack.
Keep the sealed, freeze-dried vial in the fridge, and out of direct light. Once you mix it with bacteriostatic water, store it refrigerated and use it within a few weeks. Don't freeze a reconstituted vial.
For the no-DAC form, people dose on an empty stomach, often before bed, because food and insulin blunt the GH release. Wait about 20 to 30 minutes before eating. The DAC form is less timing-sensitive since it stays in your system for days. CJC-1295 isn't an oral peptide, so skip the capsule versions.
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